We are seeking a highly motivated postdoctoral fellow to join the Max Tischfield lab. Our research revolves around two key areas: (1) understanding circuit mechanisms and the neuropathogenesis of Tourette syndrome and related conditions (OCD, ADHD, ASD) using genetic mouse models; (2) the development and functions of brain waste clearance systems, specifically understanding the development, integration, and maintenance of meningeal lymphatic vessels with the glymphatic system. Applicants have the opportunity to work in EITHER focus area, but we are especially interested in candidates who wish to work in the field of Tourette's and related neurodevelopmental/neuropsychiatric conditions. We have engineered seven novel mouse models expressing human mutations in high confidence Tourette genes. Current projects involve studying the effects on cortico-striatal signaling, dopamine dysregulation, and how cholinergic interneurons affect these processes. Our lab combines multiple approaches including human/mouse genetics, mouse behavior and operant conditioning, slice patch clamp electrophysiology, in vivo imaging, and computer vision as part of a collaborative, multi-PI team setting.

Candidates should have a recent Ph.D. in neurobiology or a related field with one or more first author publications in internationally recognized peer-reviewed journals. Candidates must have effective communication skills and be highly motivated, self-driven, creative, and interactive, with the ability to work collaboratively and independently. A proven record of accomplishment with mouse genetics, histology, rodent stereotaxic brain injections, electrophysiology, optogenetics, and/or mouse behavior is preferred. Experience with script writing and coding skills is a plus. This position requires experience and willingness to work with mice. Salary will be negotiable, competitive, and commensurate with experience. Applicants should send a CV, a cover letter with a description of their research background, and the names and contact information of three references.